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Notch transactivates Rheb to maintain the multipotency of TSC-null cells
Differentiation abnormalities are a hallmark of tuberous sclerosis complex (TSC) manifestations; however, the genesis of these abnormalities remains unclear. Here we report on mechanisms controlling the multi-lineage, early neuronal progenitor and neural stem-like cell characteristics of lymphangiol...
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出版年: | Nat Commun |
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主要な著者: | , , , , , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Nature Publishing Group UK
2017
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705704/ https://ncbi.nlm.nih.gov/pubmed/29184052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01845-1 |
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