Preventive Trichuris suis ova (TSO) treatment protects immunocompetent rabbits from DSS colitis but may be detrimental under conditions of immunosuppression

Trichuris suis ova (TSO) have been tested for therapeutic application in inflammatory bowel diseases (IBD) yet understanding of the underlying mechanisms and safety in an immunocompromised host is limited due to lack of a suitable animal model. We used a recently established rabbit model of dextran...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leonardi, Irina, Gerstgrasser, Alexandra, Schmidt, Thomas S. B., Nicholls, Flora, Tewes, Bernhard, Greinwald, Roland, von Mering, Christian, Rogler, Gerhard, Frey-Wagner, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705695/
https://ncbi.nlm.nih.gov/pubmed/29184071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16287-4
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