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Preventive Trichuris suis ova (TSO) treatment protects immunocompetent rabbits from DSS colitis but may be detrimental under conditions of immunosuppression

Trichuris suis ova (TSO) have been tested for therapeutic application in inflammatory bowel diseases (IBD) yet understanding of the underlying mechanisms and safety in an immunocompromised host is limited due to lack of a suitable animal model. We used a recently established rabbit model of dextran...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Leonardi, Irina, Gerstgrasser, Alexandra, Schmidt, Thomas S. B., Nicholls, Flora, Tewes, Bernhard, Greinwald, Roland, von Mering, Christian, Rogler, Gerhard, Frey-Wagner, Isabelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705695/
https://ncbi.nlm.nih.gov/pubmed/29184071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16287-4
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