Preventive Trichuris suis ova (TSO) treatment protects immunocompetent rabbits from DSS colitis but may be detrimental under conditions of immunosuppression

Trichuris suis ova (TSO) have been tested for therapeutic application in inflammatory bowel diseases (IBD) yet understanding of the underlying mechanisms and safety in an immunocompromised host is limited due to lack of a suitable animal model. We used a recently established rabbit model of dextran...

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Publicat a:Sci Rep
Autors principals: Leonardi, Irina, Gerstgrasser, Alexandra, Schmidt, Thomas S. B., Nicholls, Flora, Tewes, Bernhard, Greinwald, Roland, von Mering, Christian, Rogler, Gerhard, Frey-Wagner, Isabelle
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705695/
https://ncbi.nlm.nih.gov/pubmed/29184071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16287-4
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