Adrenomedullin protects Leydig cells against lipopolysaccharide-induced oxidative stress and inflammatory reaction via MAPK/NF-κB signalling pathways

This study aimed to explore the possible benefits of adrenomedullin (ADM) in preventing oxidative stress and inflammation by using an in vitro primary culture model of rat Leydig cells exposed to lipopolysaccharide (LPS). Cell proliferation was detected through CCK-8 and BrdU incorporation assays. R...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Hu, Wei, Shi, Lei, Li, Ming-yong, Zhou, Pang-hu, Qiu, Bo, Yin, Ke, Zhang, Hui-hui, Gao, Yong, Kang, Ran, Qin, Song-lin, Ning, Jin-zhuo, Wang, Wei, Zhang, Li-jun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705677/
https://ncbi.nlm.nih.gov/pubmed/29184072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16008-x
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