Adrenomedullin protects Leydig cells against lipopolysaccharide-induced oxidative stress and inflammatory reaction via MAPK/NF-κB signalling pathways

This study aimed to explore the possible benefits of adrenomedullin (ADM) in preventing oxidative stress and inflammation by using an in vitro primary culture model of rat Leydig cells exposed to lipopolysaccharide (LPS). Cell proliferation was detected through CCK-8 and BrdU incorporation assays. R...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hu, Wei, Shi, Lei, Li, Ming-yong, Zhou, Pang-hu, Qiu, Bo, Yin, Ke, Zhang, Hui-hui, Gao, Yong, Kang, Ran, Qin, Song-lin, Ning, Jin-zhuo, Wang, Wei, Zhang, Li-jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705677/
https://ncbi.nlm.nih.gov/pubmed/29184072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16008-x
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