Protective Effect of Adrenomedullin on Rat Leydig Cells from Lipopolysaccharide-Induced Inflammation and Apoptosis via the PI3K/Akt Signaling Pathway ADM on Rat Leydig Cells from Inflammation and Apoptosis

This study was carried out to investigate whether ADM can modulate LPS-induced inflammation and apoptosis in rat Leydig cells. Leydig cells were treated with ADM before LPS-induced cytotoxicity. We determined the concentrations of ROS, MDA, GSH, LDH, and testosterone and the MMP. The mRNA levels of...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Zhou, Pang-Hu, Hu, Wei, Zhang, Xiao-Bin, Wang, Wei, Zhang, Li-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861819/
https://ncbi.nlm.nih.gov/pubmed/27212810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7201549
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