Angiogenic Imbalance and Diminished Matrix Metalloproteinase-2 and -9 Underlie Regional Decreases in Uteroplacental Vascularization and Feto-placental Growth in Hypertensive Pregnancy

Preeclampsia is a form of hypertension-in-pregnancy (HTN-Preg) with unclear mechanism. Generalized reduction of uterine perfusion pressure (RUPP) could be an initiating event leading to uteroplacental ischemia, angiogenic imbalance, and HTN-Preg. Additional regional differences in uteroplacental blo...

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Vydáno v:Biochem Pharmacol
Hlavní autoři: Dias-Junior, Carlos A., Chen, Juanjuan, Cui, Ning, Chiang, Charles L., Zhu, Minglin, Ren, Zongli, Possomato-Vieira, Jose S., Khalil, Raouf A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705464/
https://ncbi.nlm.nih.gov/pubmed/28912068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.09.005
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