Placental growth factor reverses decreased vascular and uteroplacental MMP-2 and MMP-9 and increased MMP-1 and MMP-7 and collagen types I and IV in hypertensive pregnancy

Preeclampsia is a complication of pregnancy manifested as maternal hypertension (HTN) and fetal intrauterine growth restriction, with unclear mechanisms. Placental ischemia increases antiangiogenic soluble fms-like tyrosine kinase-1 (sFlt-1) relative to angiogenic placental growth factor (PlGF); how...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Ren, Zongli, Cui, Ning, Zhu, Minglin, Khalil, Raouf A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087780/
https://ncbi.nlm.nih.gov/pubmed/29569955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00045.2018
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