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Decreased Homodimerization and Increased TIMP-1 Complexation of Uteroplacental and Uterine Arterial Matrix Metalloproteinase-9 during Hypertension-in-Pregnancy

Preeclampsia is a complication of pregnancy manifested as hypertension-in-pregnancy (HTN-Preg) and often intrauterine growth restriction (IUGR). Placental ischemia could be an initiating event, but the molecular mechanisms are unclear. To test the hypothesis that dimerization of matrix metalloprotei...

詳細記述

保存先:
書誌詳細
出版年:Biochem Pharmacol
主要な著者: Chen, Juanjuan, Ren, Zongli, Zhu, Minglin, Khalil, Raouf A.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516730/
https://ncbi.nlm.nih.gov/pubmed/28506758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.05.005
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