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Immunobiology of the IL-15-IL-15Rα Complex as an Antitumor and Antiviral Agent

Interleukin (IL)-15 is essential for natural killer (NK), NKT and memory (m) CD8(+) T cell development and function, and is currently under investigation as an immunotherapeutic agent for the treatment of cancer. Recently, the creation of IL-15 superagonist by complexing IL-15 and its high affinity...

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Detalhes bibliográficos
Publicado no:Cytokine Growth Factor Rev
Principais autores: Guo, Yin, Luan, Liming, Patil, Naeem K., Sherwood, Edward R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705392/
https://ncbi.nlm.nih.gov/pubmed/28888485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2017.08.002
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