Carregant...
Insights into immune tolerance from AIRE deficiency
AIRE is a well-established master regulator of central tolerance. It plays an essential role in driving expression of tissue-specific antigens in the thymus and shaping the development of positively selected T-cells. Humans and mice with compromised or absent AIRE function have markedly variable phe...
Guardat en:
| Publicat a: | Curr Opin Immunol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705335/ https://ncbi.nlm.nih.gov/pubmed/29065385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2017.10.003 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|