Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2

The “brain-gut” peptide ghrelin, which mediates food-seeking behaviors, is recognized as a very strong endogenous modulator of dopamine (DA) signaling. Ghrelin binds the G protein-coupled receptor GHSR1a, and administration of ghrelin increases the rewarding properties of psychostimulants while ghre...

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Udgivet i:Synapse
Main Authors: Toth, Krisztian, Slosky, Lauren M., Pack, Thomas F., Urs, Nikhil M., Boone, Peter, Mao, Lan, Abraham, Dennis, Caron, Marc G., Barak, Lawrence S.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705267/
https://ncbi.nlm.nih.gov/pubmed/28941296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.22012
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