Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs

[Image: see text] G-protein-coupled receptors (GPCRs) can bias signaling through distinct biochemical pathways that originate from G-protein/receptor and β-arrestin/receptor complexes. Receptor conformations supporting β-arrestin engagement depend on multiple receptor determinants. Using ghrelin rec...

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Bibliografische gegevens
Gepubliceerd in:ACS Pharmacol Transl Sci
Hoofdauteurs: Toth, Krisztian, Nagi, Karim, Slosky, Lauren M., Rochelle, Lauren, Ray, Caroline, Kaur, Suneet, Shenoy, Sudha K., Caron, Marc G., Barak, Larry S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2019
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088988/
https://ncbi.nlm.nih.gov/pubmed/32259059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00018
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