A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis

PRDM9 binding localizes almost all meiotic recombination sites in humans and mice. However, most PRDM9-bound loci do not become recombination hotspots. To explore factors that affect binding and subsequent recombination outcomes, we mapped human PRDM9 binding sites in a transfected human cell line a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Altemose, Nicolas, Noor, Nudrat, Bitoun, Emmanuelle, Tumian, Afidalina, Imbeault, Michael, Chapman, J Ross, Aricescu, A Radu, Myers, Simon R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Chromosomes and Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705219/
https://ncbi.nlm.nih.gov/pubmed/29072575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28383
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados