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Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq

R-loops are features of chromatin consisting of a strand of DNA hybridized to RNA, as well as the expelled complementary DNA strand. R-loops are enriched at promoters where they have recently been shown to have important roles in modifying gene expression. However, the location of promoter-associate...

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Publicat a:eLife
Autors principals: Dumelie, Jason G, Jaffrey, Samie R
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705216/
https://ncbi.nlm.nih.gov/pubmed/29072160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28306
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