Cyclin D1 restrains oncogene-induced autophagy by regulating the AMPK-LKB1 signaling axis

Autophagy activated after DNA damage or other stresses mitigates cellular damage by removing damaged proteins, lipids and organelles. Activation of the master metabolic kinase AMPK enhances autophagy. Here we report that cyclin D1 restrains autophagy by modulating the activation of AMPK. In cell mod...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Casimiro, Mathew C., Di Sante, Gabriele, Di Rocco, Agnese, Loro, Emanuele, Pupo, Claudia, Pestell, Timothy G., Bisetto, Sara, Velasco-Velázquez, Marco A., Jiao, Xuanmao, Li, Zhiping, Kusminski, Christine M., Seifert, Erin L., Wang, Chenguang, Ly, Daniel, Zheng, Bin, Shen, Che-Hung, Scherer, Philipp E., Pestell, Richard G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705201/
https://ncbi.nlm.nih.gov/pubmed/28522753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0425
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak