Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers

Lipid nanoparticles (LNPs) or liposomes are the most widely used drug carriers for nanomedicines. The size of LNPs is one of the essential factors affecting drug delivery efficiency and therapeutic efficiency. Here, we demonstrated the effect of lipid concentration and mixing performance on the LNP...

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Udgivet i:PLoS One
Main Authors: Maeki, Masatoshi, Fujishima, Yuka, Sato, Yusuke, Yasui, Takao, Kaji, Noritada, Ishida, Akihiko, Tani, Hirofumi, Baba, Yoshinobu, Harashima, Hideyoshi, Tokeshi, Manabu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705116/
https://ncbi.nlm.nih.gov/pubmed/29182626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187962
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