Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers

Lipid nanoparticles (LNPs) or liposomes are the most widely used drug carriers for nanomedicines. The size of LNPs is one of the essential factors affecting drug delivery efficiency and therapeutic efficiency. Here, we demonstrated the effect of lipid concentration and mixing performance on the LNP...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Maeki, Masatoshi, Fujishima, Yuka, Sato, Yusuke, Yasui, Takao, Kaji, Noritada, Ishida, Akihiko, Tani, Hirofumi, Baba, Yoshinobu, Harashima, Hideyoshi, Tokeshi, Manabu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705116/
https://ncbi.nlm.nih.gov/pubmed/29182626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187962
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