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Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells

Observed variations in drug responses among patients may result from differences in heritable genetic traits or from alterations in the epigenetic regulation of drug metabolizing enzymes and transporters (DMETs). MicroRNAs (miRNAs), a group of small non-coding RNAs, provide an epigenetic mechanism f...

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Détails bibliographiques
Publié dans:Biochem Pharmacol
Auteurs principaux: Yu, Dianke, Tolleson, William H., Knox, Bridgett, Jin, Yaqiong, Guo, Lei, Guo, Yongli, Kadlubar, Susan A., Ning, Baitang
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705000/
https://ncbi.nlm.nih.gov/pubmed/26428001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.09.020
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