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Role of the endothelial caveolae microdomain in shear stress–mediated coronary vasorelaxation

In this study, we determined the role of caveolae and the ionic mechanisms that mediate shear stress–mediated vasodilation (SSD). We found that both TRPV4 and SK channels are targeted to caveolae in freshly isolated bovine coronary endothelial cells (BCECs) and that TRPV4 and KCa2.3 (SK3) channels a...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Lu, Tong, Wang, Xiao-Li, Chai, Qiang, Sun, Xiaojing, Sieck, Garry C., Katusic, Zvonimir S., Lee, Hon-Chi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704482/
https://ncbi.nlm.nih.gov/pubmed/28924052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786152
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