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Role of the endothelial caveolae microdomain in shear stress–mediated coronary vasorelaxation
In this study, we determined the role of caveolae and the ionic mechanisms that mediate shear stress–mediated vasodilation (SSD). We found that both TRPV4 and SK channels are targeted to caveolae in freshly isolated bovine coronary endothelial cells (BCECs) and that TRPV4 and KCa2.3 (SK3) channels a...
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| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704482/ https://ncbi.nlm.nih.gov/pubmed/28924052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786152 |
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