Epigenetic modifications of the VGF gene in human non-small cell lung cancer tissues pave the way towards enhanced expression

Hwang et al. recently showed that VGF substantially contributes to the resistance of human lung cancer cells towards epidermal growth factor receptor kinase inhibitors. This was further linked to enhanced epithelial–mesenchymal transition. Here, we demonstrate that VGF is epigenetically modified in...

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Bibliografske podrobnosti
izdano v:Clin Epigenetics
Main Authors: Marwitz, Sebastian, Heinbockel, Lena, Scheufele, Swetlana, Nitschkowski, Dörte, Kugler, Christian, Perner, Sven, Reck, Martin, Ammerpohl, Ole, Goldmann, Torsten
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Letter to the Editor
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704452/
https://ncbi.nlm.nih.gov/pubmed/29209432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0423-6
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