Antimicrobial peptides and the enteric mucus layer act in concert to protect the intestinal mucosa

di Dupont, Aline, Heinbockel, Lena, Brandenburg, Klaus, Hornef, Mathias W
Pubblicato in Gut Microbes (2014)

Synthetic antimicrobial and LPS-neutralising peptides suppress inflammatory and immune responses in skin cells and promote keratinocyte migration

di Pfalzgraff, Anja, Heinbockel, Lena, Su, Qi, Gutsmann, Thomas, Brandenburg, Klaus, Weindl, Günther
Pubblicato in Sci Rep (2016)

Biophysical analysis of the interaction of the serum protein human β(2)GPI with bacterial lipopolysaccharide

di Gries, Anna, Prassl, Ruth, Fukuoka, Satoshi, Rössle, Manfred, Kaconis, Yani, Heinbockel, Lena, Gutsmann, Thomas, Brandenburg, Klaus
Pubblicazione 2014

Self-Organisation, Thermotropic and Lyotropic Properties of Glycolipids Related to their Biological Implications

di Garidel, Patrick, Kaconis, Yani, Heinbockel, Lena, Wulf, Matthias, Gerber, Sven, Munk, Ariane, Vill, Volkmar, Brandenburg, Klaus
Pubblicato in Open Biochem J (2015)

Biophysical Mechanisms of the Neutralization of Endotoxins by Lipopolyamines

di Sil, Diptesh, Heinbockel, Lena, Kaconis, Yani, Rössle, Manfred, Garidel, Patrick, Gutsmann, Thomas, David, Sunil A, Brandenburg, Klaus
Pubblicazione 2013

The anti-inflammatory effect of the synthetic antimicrobial peptide 19-2.5 in a murine sepsis model: a prospective randomized study

di Schuerholz, Tobias, Doemming, Sabine, Hornef, Mathias, Martin, Lukas, Simon, Tim-Philipp, Heinbockel, Lena, Brandenburg, Klaus, Marx, Gernot
Pubblicazione 2013

Antimicrobial endotoxin‐neutralizing peptides promote keratinocyte migration via P2X7 receptor activation and accelerate wound healing in vivo

di Pfalzgraff, Anja, Bárcena‐Varela, Sergio, Heinbockel, Lena, Gutsmann, Thomas, Brandenburg, Klaus, Martinez‐de‐Tejada, Guillermo, Weindl, Günther
Pubblicato in Br J Pharmacol (2018)

Epigenetic modifications of the VGF gene in human non-small cell lung cancer tissues pave the way towards enhanced expression

di Marwitz, Sebastian, Heinbockel, Lena, Scheufele, Swetlana, Nitschkowski, Dörte, Kugler, Christian, Perner, Sven, Reck, Martin, Ammerpohl, Ole, Goldmann, Torsten
Pubblicato in Clin Epigenetics (2017)

The Synthetic Antimicrobial Peptide 19-2.5 Interacts with Heparanase and Heparan Sulfate in Murine and Human Sepsis

di Martin, Lukas, De Santis, Rebecca, Koczera, Patrick, Simons, Nadine, Haase, Hajo, Heinbockel, Lena, Brandenburg, Klaus, Marx, Gernot, Schuerholz, Tobias
Pubblicato in PLoS One (2015)

Fountain of youth for squamous cell carcinomas? On the epigenetic age of non‐small cell lung cancer and corresponding tumor‐free lung tissues

di Marwitz, Sebastian, Heinbockel, Lena, Scheufele, Swetlana, Kugler, Christian, Reck, Martin, Rabe, Klaus F., Perner, Sven, Goldmann, Torsten, Ammerpohl, Ole
Pubblicato in Int J Cancer (2018)

Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications

di Malgorzata-Miller, Gosia, Heinbockel, Lena, Brandenburg, Klaus, van der Meer, Jos W. M., Netea, Mihai G., Joosten, Leo A. B.
Pubblicato in Sci Rep (2016)

Peptide 19-2.5 Inhibits Heparan Sulfate-Triggered Inflammation in Murine Cardiomyocytes Stimulated with Human Sepsis Serum

di Martin, Lukas, Schmitz, Susanne, De Santis, Rebecca, Doemming, Sabine, Haase, Hajo, Hoeger, Janine, Heinbockel, Lena, Brandenburg, Klaus, Marx, Gernot, Schuerholz, Tobias
Pubblicato in PLoS One (2015)

Identification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease

di Heinbockel, Lena, Marwitz, Sebastian, Schromm, Andra B, Watz, Henrik, Kugler, Christian, Ammerpohl, Ole, Schnepf, Karoline, Rabe, Klaus F, Droemann, Daniel, Goldmann, Torsten
Pubblicato in Int J Chron Obstruct Pulmon Dis (2018)

Inhibition of Lipopolysaccharide- and Lipoprotein-Induced Inflammation by Antitoxin Peptide Pep19-2.5

di Heinbockel, Lena, Weindl, Günther, Martinez-de-Tejada, Guillermo, Correa, Wilmar, Sanchez-Gomez, Susana, Bárcena-Varela, Sergio, Goldmann, Torsten, Garidel, Patrick, Gutsmann, Thomas, Brandenburg, Klaus
Pubblicato in Front Immunol (2018)

Inactivation of Bacteria by γ-Irradiation to Investigate the Interaction with Antimicrobial Peptides

di Correa, Wilmar, Brandenburg, Julius, Behrends, Jochen, Heinbockel, Lena, Reiling, Norbert, Paulowski, Laura, Schwudke, Dominik, Stephan, Kerstin, Martinez-de-Tejada, Guillermo, Brandenburg, Klaus, Gutsmann, Thomas
Pubblicato in Biophys J (2019)

Anti-Infective and Anti-Inflammatory Mode of Action of Peptide 19-2.5

di Heinbockel, Lena, Weindl, Günther, Correa, Wilmar, Brandenburg, Julius, Reiling, Norbert, Wiesmüller, Karl-Heinz, Schürholz, Tobias, Gutsmann, Thomas, Martinez de Tejada, Guillermo, Mauss, Karl, Brandenburg, Klaus
Pubblicato in Int J Mol Sci (2021)

Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis

di Heinbockel, Lena, Marwitz, Sebastian, Barcena Varela, Sergio, Ferrer-Espada, Raquel, Reiling, Norbert, Goldmann, Torsten, Gutsmann, Thomas, Mier, Walter, Schürholz, Tobias, Drömann, Daniel, Brandenburg, Klaus, Martinez de Tejada, Guillermo
Pubblicato in PLoS One (2015)

Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits

di Bárcena-Varela, Sergio, Martínez-de-Tejada, Guillermo, Martin, Lukas, Schuerholz, Tobias, Gil-Royo, Ana Gloria, Fukuoka, Satoshi, Goldmann, Torsten, Droemann, Daniel, Correa, Wilmar, Gutsmann, Thomas, Brandenburg, Klaus, Heinbockel, Lena
Pubblicato in Exp Mol Med (2017)

Preclinical Investigations Reveal the Broad-Spectrum Neutralizing Activity of Peptide Pep19-2.5 on Bacterial Pathogenicity Factors

di Heinbockel, Lena, Sánchez-Gómez, Susana, Martinez de Tejada, Guillermo, Dömming, Sabine, Brandenburg, Julius, Kaconis, Yani, Hornef, Mathias, Dupont, Aline, Marwitz, Sebastian, Goldmann, Torsten, Ernst, Martin, Gutsmann, Thomas, Schürholz, Tobias, Brandenburg, Klaus
Pubblicazione 2013

Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides

di de Tejada, Guillermo Martinez, Heinbockel, Lena, Ferrer-Espada, Raquel, Heine, Holger, Alexander, Christian, Bárcena-Varela, Sergio, Goldmann, Torsten, Correa, Wilmar, Wiesmüller, Karl-Heinz, Gisch, Nicolas, Sánchez-Gómez, Susana, Fukuoka, Satoshi, Schürholz, Tobias, Gutsmann, Thomas, Brandenburg, Klaus
Pubblicato in Sci Rep (2015)