Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits

Sepsis, which is induced by severe bacterial infections, is a major cause of death worldwide, and therapies combating the disease are urgently needed. Because many drugs have failed in clinical trials despite their efficacy in mouse models, the development of reliable animal models of sepsis is in g...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Bárcena-Varela, Sergio, Martínez-de-Tejada, Guillermo, Martin, Lukas, Schuerholz, Tobias, Gil-Royo, Ana Gloria, Fukuoka, Satoshi, Goldmann, Torsten, Droemann, Daniel, Correa, Wilmar, Gutsmann, Thomas, Brandenburg, Klaus, Heinbockel, Lena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519016/
https://ncbi.nlm.nih.gov/pubmed/28620220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.75
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