Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits

Sepsis, which is induced by severe bacterial infections, is a major cause of death worldwide, and therapies combating the disease are urgently needed. Because many drugs have failed in clinical trials despite their efficacy in mouse models, the development of reliable animal models of sepsis is in g...

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Bibliographische Detailangaben
Veröffentlicht in:Exp Mol Med
Hauptverfasser: Bárcena-Varela, Sergio, Martínez-de-Tejada, Guillermo, Martin, Lukas, Schuerholz, Tobias, Gil-Royo, Ana Gloria, Fukuoka, Satoshi, Goldmann, Torsten, Droemann, Daniel, Correa, Wilmar, Gutsmann, Thomas, Brandenburg, Klaus, Heinbockel, Lena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519016/
https://ncbi.nlm.nih.gov/pubmed/28620220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.75
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