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Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits

Sepsis, which is induced by severe bacterial infections, is a major cause of death worldwide, and therapies combating the disease are urgently needed. Because many drugs have failed in clinical trials despite their efficacy in mouse models, the development of reliable animal models of sepsis is in g...

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Dettagli Bibliografici
Pubblicato in:Exp Mol Med
Autori principali: Bárcena-Varela, Sergio, Martínez-de-Tejada, Guillermo, Martin, Lukas, Schuerholz, Tobias, Gil-Royo, Ana Gloria, Fukuoka, Satoshi, Goldmann, Torsten, Droemann, Daniel, Correa, Wilmar, Gutsmann, Thomas, Brandenburg, Klaus, Heinbockel, Lena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519016/
https://ncbi.nlm.nih.gov/pubmed/28620220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.75
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