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Reverse Transcriptase Mechanism of Somatic Hypermutation: 60 Years of Clonal Selection Theory

The evidence for the reverse transcriptase mechanism of somatic hypermutation is substantial and multifactorial. In this 60th anniversary year of the publication of Sir MacFarlane Burnet’s Clonal Selection Theory, the evidence is briefly reviewed and updated.

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Detalhes bibliográficos
Publicado no:Front Immunol
Autor principal: Steele, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704389/
https://ncbi.nlm.nih.gov/pubmed/29218047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01611
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