Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails

BACKGROUND: Stable insertion of the retroviral DNA genome into host chromatin requires the functional association between the intasome (integrase·viral DNA complex) and the nucleosome. The data from the literature suggest that direct protein–protein contacts between integrase and histones may be inv...

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發表在:Retrovirology
Main Authors: Benleulmi, Mohamed S., Matysiak, Julien, Robert, Xavier, Miskey, Csaba, Mauro, Eric, Lapaillerie, Delphine, Lesbats, Paul, Chaignepain, Stéphane, Henriquez, Daniel R., Calmels, Christina, Oladosu, Oyindamola, Thierry, Eloïse, Leon, Oscar, Lavigne, Marc, Andreola, Marie-Line, Delelis, Olivier, Ivics, Zoltán, Ruff, Marc, Gouet, Patrice, Parissi, Vincent
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704366/
https://ncbi.nlm.nih.gov/pubmed/29179726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0378-x
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