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Evolving Significance and Future Relevance of Anti-Angiogenic Activity of mTOR Inhibitors in Cancer Therapy

mTOR inhibitors have demonstrated remarkable anti-tumor activity in experimental models, mainly by reducing cancer cell growth and tumor angiogenesis. Their use in cancer patients as monotherapy has, however, generated only limited benefits, increasing median overall survival by only a few months. L...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Faes, Seraina, Santoro, Tania, Demartines, Nicolas, Dormond, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704170/
https://ncbi.nlm.nih.gov/pubmed/29104248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9110152
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