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Mechanistic Target of Rapamycin Inhibitors in Renal Cell Carcinoma: Potential, Limitations, and Perspectives

Several elements highlight the importance of the mechanistic target of rapamycin (mTOR) in the biology of renal cell carcinoma (RCC). mTOR signaling pathway is indeed frequently activated in RCC, inducing cancer cell proliferation and survival. In addition, mTOR promotes tumor angiogenesis and regul...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Faes, Seraina, Demartines, Nicolas, Dormond, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005589/
https://ncbi.nlm.nih.gov/pubmed/33791295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.636037
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