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Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors
The inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) by chemical inhibitors, such as rapamycin, has demonstrated anti-cancer activity in preclinical and clinical trials. Their efficacy is, however, limited and tumors eventually relapse through resistance formation. In this study,...
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Foilsithe in: | Oncotarget |
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Main Authors: | , , , , , , , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Impact Journals LLC
2016
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5095030/ https://ncbi.nlm.nih.gov/pubmed/27153561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9134 |
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