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Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors
The inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) by chemical inhibitors, such as rapamycin, has demonstrated anti-cancer activity in preclinical and clinical trials. Their efficacy is, however, limited and tumors eventually relapse through resistance formation. In this study,...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5095030/ https://ncbi.nlm.nih.gov/pubmed/27153561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9134 |
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