Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors

The inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) by chemical inhibitors, such as rapamycin, has demonstrated anti-cancer activity in preclinical and clinical trials. Their efficacy is, however, limited and tumors eventually relapse through resistance formation. In this study,...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Faes, Seraina, Planche, Anne, Uldry, Emilie, Santoro, Tania, Pythoud, Catherine, Stehle, Jean-Christophe, Horlbeck, Janine, Letovanec, Igor, Riggi, Nicolo, Datta, Dipak, Demartines, Nicolas, Dormond, Olivier
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095030/
https://ncbi.nlm.nih.gov/pubmed/27153561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9134
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