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Role of the N-acetylation polymorphism in solithromycin metabolism
AIM: Solithromycin is a new macrolide antibiotic for the potential treatment of bacterial pneumonia. MATERIALS & METHODS: Solithromycin N-acetylation by human NAT1 and NAT2 was investigated following recombinant expression in yeast and in cryopreserved human hepatocytes from rapid, intermediate...
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| Publicado no: | Pharmacogenomics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Future Medicine Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704091/ https://ncbi.nlm.nih.gov/pubmed/28625123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0045 |
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