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Role of the human N-acetyltransferase 2 genetic polymorphism in metabolism and genotoxicity of 4, 4’-methylenedianiline
4, 4’-methylenedianiline (MDA) is used extensively as a curing agent in the production of elastomers and is classified as reasonably anticipated to be a human carcinogen based on sufficient evidence in animal experiments. Human N-acetyltransferase 1 (NAT1) and 2 (NAT2) catalyze the N-acetylation of...
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| Publicado no: | Arch Toxicol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6713601/ https://ncbi.nlm.nih.gov/pubmed/31292670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02516-4 |
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