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Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

Dysfunction of the oxidative phosphorylation (OXPHOS) system is a major cause of human disease and the cellular consequences are highly complex. Here, we present comparative analyses of mitochondrial proteomes, cellular transcriptomes and targeted metabolomics of five knockout mouse strains deficien...

詳細記述

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書誌詳細
出版年:eLife
主要な著者: Kühl, Inge, Miranda, Maria, Atanassov, Ilian, Kuznetsova, Irina, Hinze, Yvonne, Mourier, Arnaud, Filipovska, Aleksandra, Larsson, Nils-Göran
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703644/
https://ncbi.nlm.nih.gov/pubmed/29132502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30952
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