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Metabolic control of regulatory T cell (Treg) survival and function by Lkb1

The metabolic programs of functionally distinct T cell subsets are tailored to their immunologic activities. While quiescent T cells use oxidative phosphorylation (OXPHOS) for energy production, and effector T cells (Teffs) rely on glycolysis for proliferation, the distinct metabolic features of reg...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: He, Nanhai, Fan, Weiwei, Henriquez, Brian, Yu, Ruth T., Atkins, Annette R., Liddle, Christopher, Zheng, Ye, Downes, Michael, Evans, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703326/
https://ncbi.nlm.nih.gov/pubmed/29109251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715363114
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