Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling

Acute kidney injury (AKI) causes severe morbidity and mortality for which new therapeutic strategies are needed. Docosahexaenoic acid (DHA), arachidonic acid (ARA), and their metabolites have various effects in kidney injury, but their molecular mechanisms are largely unknown. Here, we report that 1...

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Zapisane w:
Opis bibliograficzny
Wydane w:Proc Natl Acad Sci U S A
Główni autorzy: Deng, Bing-Qing, Luo, Ying, Kang, Xin, Li, Chang-Bin, Morisseau, Christophe, Yang, Jun, Lee, Kin Sing Stephen, Huang, Jian, Hu, Da-Yong, Wu, Ming-Yu, Peng, Ai, Hammock, Bruce D., Liu, Jun-Yan
Format: Artigo
Język:Inglês
Wydane: National Academy of Sciences 2017
Hasła przedmiotowe:
Biological Sciences
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703276/
https://ncbi.nlm.nih.gov/pubmed/29109264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705615114
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