Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling

Acute kidney injury (AKI) causes severe morbidity and mortality for which new therapeutic strategies are needed. Docosahexaenoic acid (DHA), arachidonic acid (ARA), and their metabolites have various effects in kidney injury, but their molecular mechanisms are largely unknown. Here, we report that 1...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Deng, Bing-Qing, Luo, Ying, Kang, Xin, Li, Chang-Bin, Morisseau, Christophe, Yang, Jun, Lee, Kin Sing Stephen, Huang, Jian, Hu, Da-Yong, Wu, Ming-Yu, Peng, Ai, Hammock, Bruce D., Liu, Jun-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703276/
https://ncbi.nlm.nih.gov/pubmed/29109264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705615114
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