L1 retrotransposition is activated by Ten-eleven-translocation protein 1 and repressed by methyl-CpG binding proteins

One of the major functions of DNA methylation is the repression of transposable elements, such as the long-interspersed nuclear element 1 (L1). The underlying mechanism(s), however, are unclear. Here, we addressed how retrotransposon activation and mobilization are regulated by methyl-cytosine modif...

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Pubblicato in:Nucleus
Autori principali: Zhang, Peng, Ludwig, Anne K., Hastert, Florian D., Rausch, Cathia, Lehmkuhl, Anne, Hellmann, Ines, Smets, Martha, Leonhardt, Heinrich, Cardoso, M. Cristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703239/
https://ncbi.nlm.nih.gov/pubmed/28524723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2017.1330238
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