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Effect of Oral Iron Repletion on Exercise Capacity in Patients with Heart Failure with Reduced Ejection Fraction and Iron Deficiency: the IRONOUT HF Randomized Clinical Trial

IMPORTANCE: Iron deficiency is present in approximately 50% of patients with heart failure with reduced left ventricular ejection fraction (HFrEF) and is an independent predictor of reduced functional capacity and mortality. However, the efficacy of inexpensive, readily available oral iron supplemen...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Lewis, Gregory D., Malhotra, Rajeev, Hernandez, Adrian F., McNulty, Steven E., Smith, Andrew, Felker, G. Michael, Tang, W.H. Wilson, LaRue, Shane J., Redfield, Margaret M., Semigran, Marc J., Givertz, Michael M., Van Buren, Peter, Whellan, David, Anstrom, Kevin J., Shah, Monica R., Desvigne-Nickens, Patrice, Butler, Javed, Braunwald, Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703044/
https://ncbi.nlm.nih.gov/pubmed/28510680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.5427
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