Effect of Oral Iron Repletion on Exercise Capacity in Patients with Heart Failure with Reduced Ejection Fraction and Iron Deficiency: the IRONOUT HF Randomized Clinical Trial

IMPORTANCE: Iron deficiency is present in approximately 50% of patients with heart failure with reduced left ventricular ejection fraction (HFrEF) and is an independent predictor of reduced functional capacity and mortality. However, the efficacy of inexpensive, readily available oral iron supplemen...

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Veröffentlicht in:JAMA
Hauptverfasser: Lewis, Gregory D., Malhotra, Rajeev, Hernandez, Adrian F., McNulty, Steven E., Smith, Andrew, Felker, G. Michael, Tang, W.H. Wilson, LaRue, Shane J., Redfield, Margaret M., Semigran, Marc J., Givertz, Michael M., Van Buren, Peter, Whellan, David, Anstrom, Kevin J., Shah, Monica R., Desvigne-Nickens, Patrice, Butler, Javed, Braunwald, Eugene
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703044/
https://ncbi.nlm.nih.gov/pubmed/28510680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.5427
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