Assessing Pharmacodynamic Interactions in Mice Using the Multistate Tuberculosis Pharmacometric and General Pharmacodynamic Interaction Models

The aim of this study was to investigate pharmacodynamic (PD) interactions in mice infected with Mycobacterium tuberculosis using population pharmacokinetics (PKs), the Multistate Tuberculosis Pharmacometric (MTP) model, and the General Pharmacodynamic Interaction (GPDI) model. Rifampicin, isoniazid...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:CPT Pharmacometrics Syst Pharmacol
Päätekijät: Chen, Chunli, Wicha, Sebastian G., de Knegt, Gerjo J., Ortega, Fatima, Alameda, Laura, Sousa, Veronica, de Steenwinkel, Jurriaan E. M., Simonsson, Ulrika S. H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702905/
https://ncbi.nlm.nih.gov/pubmed/28657202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12226
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