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Interphotoreceptor retinoid–binding protein removes all-trans-retinol and retinal from rod outer segments, preventing lipofuscin precursor formation
Interphotoreceptor retinoid–binding protein (IRBP) is a specialized lipophilic carrier that binds the all-trans and 11-cis isomers of retinal and retinol, and this facilitates their transport between photoreceptors and cells in the retina. One of these retinoids, all-trans-retinal, is released in th...
Enregistré dans:
| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702674/ https://ncbi.nlm.nih.gov/pubmed/28972139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.795187 |
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