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All-trans retinal levels and formation of lipofuscin precursors after bleaching in rod photoreceptors from wild type and Abca4(−/−) mice
The accumulation of lipofuscin in the cells of the retinal pigment epithelium (RPE) is thought to play an important role in the development and progression of degenerative diseases of the retina. The bulk of RPE lipofuscin originates in reactions of the rhodopsin chromophore, retinal, with component...
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| Опубликовано в: : | Exp Eye Res |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5390775/ https://ncbi.nlm.nih.gov/pubmed/28219732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2017.02.007 |
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