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The nucleosomal surface is the main target of histone ADP-ribosylation in response to DNA damage

ADP-ribosylation is a protein post-translational modification catalyzed by ADP-ribose transferases (ARTs). ART activity is critical in mediating many cellular processes, and is required for DNA damage repair. All five histone proteins are extensively ADP-ribosylated by ARTs upon induction of DNA dam...

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Bibliographic Details
Published in:Mol Biosyst
Main Authors: Karch, Kelly R., Langelier, Marie-France, Pascal, John M., Garcia, Benjamin A.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702540/
https://ncbi.nlm.nih.gov/pubmed/29058739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7mb00498b
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