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Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine
Intestinal Paneth cells limit bacterial invasion by secreting antimicrobial proteins including lysozyme. However, invasive pathogens can disrupt the Golgi apparatus, interfering with secretion and compromising intestinal antimicrobial defense. Here we show that during bacterial infection, lysozyme i...
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| Publicado en: | Science |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702267/ https://ncbi.nlm.nih.gov/pubmed/28751470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aal4677 |
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