Loss of Paneth cell autophagy causes acute susceptibility to Toxoplasma gondii-mediated inflammation

The protozoan parasite Toxoplasma gondii triggers severe small intestinal immunopathology characterized by IFN-γ- and intestinal microbiota-mediated inflammation, Paneth cell loss and bacterial dysbiosis. Paneth cells are a prominent secretory epithelial cell type that reside at the base of intestin...

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Dades bibliogràfiques
Publicat a:Cell Host Microbe
Autors principals: Burger, Elise, Araujo, Alessandra, López-Yglesias, Américo, Rajala, Michael W., Geng, Linda, Levine, Beth, Hooper, Lora V., Burstein, Ezra, Yarovinsky, Felix
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6179445/
https://ncbi.nlm.nih.gov/pubmed/29358083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.01.001
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