An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial

BACKGROUND: Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the optimal dose of fluoroquinolones as part of the regimen has not been defined. M...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Bouton, Tara C., Phillips, Patrick P. J., Mitnick, Carole D., Peloquin, Charles A., Eisenach, Kathleen, Patientia, Ramonde F., Lecca, Leonid, Gotuzzo, Eduardo, Gandhi, Neel R., Butler, Donna, Diacon, Andreas H., Martel, Bruno, Santillan, Juan, Hunt, Kathleen Robergeau, Vargas, Dante, von Groote-Bidlingmaier, Florian, Seas, Carlos, Dianis, Nancy, Moreno-Martinez, Antonio, Horsburgh, C. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702225/
https://ncbi.nlm.nih.gov/pubmed/29178937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-2292-x
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