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Mosaic autosomal aneuploidies are detectable from single-cell RNAseq data
BACKGROUND: Aneuploidies are copy number variants that affect entire chromosomes. They are seen commonly in cancer, embryonic stem cells, human embryos, and in various trisomic diseases. Aneuploidies frequently affect only a subset of cells in a sample; this is known as “mosaic” aneuploidy. A cell t...
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| Опубликовано в: : | BMC Genomics |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5702132/ https://ncbi.nlm.nih.gov/pubmed/29178830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4253-x |
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