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Viral Cre-LoxP tools aid genome engineering in mammalian cells

BACKGROUND: Targeted nucleases have transformed genome editing technology, providing more efficient methods to make targeted changes in mammalian genome. In parallel, there is an increasing demand of Cre-LoxP technology for complex genome manipulation such as large deletion, addition, gene fusion an...

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Dades bibliogràfiques
Publicat a:J Biol Eng
Autors principals: Sengupta, Ranjita, Mendenhall, Amy, Sarkar, Nandita, Mukherjee, Chandreyee, Afshari, Amirali, Huang, Joseph, Lu, Biao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702101/
https://ncbi.nlm.nih.gov/pubmed/29204184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-017-0087-y
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