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Viral Cre-LoxP tools aid genome engineering in mammalian cells

BACKGROUND: Targeted nucleases have transformed genome editing technology, providing more efficient methods to make targeted changes in mammalian genome. In parallel, there is an increasing demand of Cre-LoxP technology for complex genome manipulation such as large deletion, addition, gene fusion an...

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Dettagli Bibliografici
Pubblicato in:J Biol Eng
Autori principali: Sengupta, Ranjita, Mendenhall, Amy, Sarkar, Nandita, Mukherjee, Chandreyee, Afshari, Amirali, Huang, Joseph, Lu, Biao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702101/
https://ncbi.nlm.nih.gov/pubmed/29204184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-017-0087-y
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