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Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome.
The cre gene of coliphage P1 encodes a 38 kDa protein which efficiently promotes both intra- and intermolecular recombination at specific 34 bp sites called loxP. To demonstrate that the Cre protein can promote DNA recombination at loxP sites resident on a mammalian chromosome, a mouse cell line was...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1989
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2783482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.1.147 |
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